Antiresorptive therapy significantly reduces fracture risk in patients with benign bone disease and skeletal-related events (SREs) in patients with bone metastases (BM). Osteonecrosis of the jaw (ONJ) is a rare but severe condition manifested as necrotic bone lesion or lesions of the jaws. ONJ has been linked to the use of potent antiresorptive agents, termed medication-related ONJ (MRONJ).

Osteonecrosis of the jaw and antiresorptive agents in benign and malignant diseases. a critical review organized by the ECTS / Anastasilakis, Athanasios D; Pepe, Jessica; Napoli, Nicola; Palermo, Andrea; Magopoulos, Christos; Khan, Aliya A; Zillikens, M Carola; Body, Jean-Jacques. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. - ISSN 1945-7197. - 107:5(2022), pp. 1441-1460. [10.1210/clinem/dgab888]

Osteonecrosis of the jaw and antiresorptive agents in benign and malignant diseases. a critical review organized by the ECTS

Pepe, Jessica;
2022

Abstract

Antiresorptive therapy significantly reduces fracture risk in patients with benign bone disease and skeletal-related events (SREs) in patients with bone metastases (BM). Osteonecrosis of the jaw (ONJ) is a rare but severe condition manifested as necrotic bone lesion or lesions of the jaws. ONJ has been linked to the use of potent antiresorptive agents, termed medication-related ONJ (MRONJ).
2022
bisphosphonates; bone metastases; denosumab; osteonecrosis of the jaw; osteoporosis; diphosphonates; humans; jaw; syndrome; bisphosphonate-associated osteonecrosis of the jaw; bone density conservation agents; bone neoplasms
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Osteonecrosis of the jaw and antiresorptive agents in benign and malignant diseases. a critical review organized by the ECTS / Anastasilakis, Athanasios D; Pepe, Jessica; Napoli, Nicola; Palermo, Andrea; Magopoulos, Christos; Khan, Aliya A; Zillikens, M Carola; Body, Jean-Jacques. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. - ISSN 1945-7197. - 107:5(2022), pp. 1441-1460. [10.1210/clinem/dgab888]
File allegati a questo prodotto
File Dimensione Formato  
Anastasilakis_Osteonecrosis_2022.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 1.87 MB
Formato Adobe PDF
1.87 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1650841
Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 39
  • ???jsp.display-item.citation.isi??? 29
social impact